| 3. Round | 05/09/2021 | FSV Gütersloh 2009 [Women] | - | VfL Wolfsburg II [Women] | 6:0 | ||||
| 4. Round | 12/09/2021 | VfL Wolfsburg II [Women] | - | 1899 Hoffenheim II [Women] | 0:0 | ||||
| 5. Round | 26/09/2021 | Bayern München II [Women] | - | VfL Wolfsburg II [Women] | 4:1 | ||||
| 6. Round | 10/10/2021 | VfL Wolfsburg II [Women] | - | Eintracht Frankfurt II [Women] | 1:2 | ||||
| 11. Round | 05/12/2021 | FC Ingolstadt 04 [Women] | - | VfL Wolfsburg II [Women] | 2:0 | ||||
| 13. Round | 19/12/2021 | SV Henstedt-Ulzburg [Women] | - | VfL Wolfsburg II [Women] | 1:2 | ||||
| 21. Round | 24/04/2022 | SG 99 Andernach [Women] | - | VfL Wolfsburg II [Women] | 3:0 | ||||
| 22. Round | 01/05/2022 | VfL Wolfsburg II [Women] | - | Borussia Bocholt [Women] | 1:0 | ||||
| 23. Round | 08/05/2022 | SV 07 Elversberg [Women] | - | VfL Wolfsburg II [Women] | 1:2 | ||||
| 24. Round | 15/05/2022 | VfL Wolfsburg II [Women] | - | FC Ingolstadt 04 [Women] | 4:1 | ||||
| 26. Round | 05/06/2022 | VfL Wolfsburg II [Women] | - | SV Henstedt-Ulzburg [Women] | 1:1 |
Germany