| 1. Round | 30/08/1980 | Chemie Schönebeck | - | SG Dynamo Eisleben | 0:5 |  |
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| 2. Round | 06/09/1980 | SG Dynamo Eisleben | - | BSG Stahl Nordwest Leipzig | 1:1 | ||||
| 3. Round | 13/09/1980 | ASG Vorwärts Dessau | - | SG Dynamo Eisleben | 0:1 | ||||
| 5. Round | 04/10/1980 | BSG Stahl Thale | - | SG Dynamo Eisleben | 3:1 | ||||
| 6. Round | 07/10/1980 | BSG Chemie Wolfen | - | SG Dynamo Eisleben | 1:1 | ||||
| 7. Round | 19/10/1980 | SG Dynamo Eisleben | - | BSG Chemie Buna Schkopau | 6:1 | ||||
| 9. Round | 08/11/1980 | SG Dynamo Eisleben | - | BSG Chemie Zeitz | 4:0 |
Germany