| 5. Round | 11/09/2022 | 1. FSV Mainz 05 [Youth B] | - | FC-Astoria Walldorf [Youth B] | 1:0 | ||||
| 6. Round | 18/09/2022 | 1. FC Saarbrücken [Youth B] | - | 1. FSV Mainz 05 [Youth B] | 0:5 |  |
|||
| 8. Round | 09/10/2022 | Karlsruher SC [Youth B] | - | 1. FSV Mainz 05 [Youth B] | 0:0 | ||||
| 9. Round | 29/10/2022 | 1. FSV Mainz 05 [Youth B] | - | 1. FC Nürnberg [Youth B] | 5:1 | ||||
| 10. Round | 05/11/2022 | Eintracht Frankfurt [Youth B] | - | 1. FSV Mainz 05 [Youth B] | 4:2 | ||||
| 11. Round | 12/11/2022 | 1. FSV Mainz 05 [Youth B] | - | Jahn Regensburg [Youth B] | 0:2 | ||||
| 13. Round | 04/12/2022 | 1. FSV Mainz 05 [Youth B] | - | SV Darmstadt 98 [Youth B] | 0:1 |  |
|||
| 14. Round | 11/12/2022 | VfB Stuttgart [Youth B] | - | 1. FSV Mainz 05 [Youth B] | 1:1 |
Germany
Morocco