| 1. Round | 15/08/2021 | VfL Wolfsburg II [Women] | - | RB Leipzig [Women] | 1:2 | ||||
| 2. Round | 29/08/2021 | MSV Duisburg [Women] | - | VfL Wolfsburg II [Women] | 1:0 | ||||
| 18. Round | 10/04/2022 | VfL Wolfsburg II [Women] | - | Bayern München II [Women] | 0:1 | ||||
| 19. Round | 20/04/2022 | Eintracht Frankfurt II [Women] | - | VfL Wolfsburg II [Women] | 2:2 | ||||
| 24. Round | 15/05/2022 | VfL Wolfsburg II [Women] | - | FC Ingolstadt 04 [Women] | 4:1 | ||||
| 25. Round | 22/05/2022 | 1. FC Nürnberg [Women] | - | VfL Wolfsburg II [Women] | 3:3 | ||||
| 26. Round | 05/06/2022 | VfL Wolfsburg II [Women] | - | SV Henstedt-Ulzburg [Women] | 1:1 |
Germany