| 3. Round | 11/09/2010 | FSV Frankfurt | - | Fortuna Düsseldorf | 1:0 | ||||
| 6. Round | 24/09/2010 | Karlsruher SC | - | FSV Frankfurt | 0:2 |  |
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| 9. Round | 23/10/2010 | FC Ingolstadt 04 | - | FSV Frankfurt | 0:1 | ||||
| 10. Round | 29/10/2010 | FSV Frankfurt | - | SC Paderborn 07 | 2:0 | ||||
| 12. Round | 13/11/2010 | FSV Frankfurt | - | 1. FC Union Berlin | 2:1 | ||||
| 14. Round | 26/11/2010 | FSV Frankfurt | - | VfL Osnabrück | 4:1 | ||||
| 19. Round | 23/01/2011 | FSV Frankfurt | - | Rot-Weiß Oberhausen | 4:0 | ||||
| 32. Round | 30/04/2011 | FSV Frankfurt | - | MSV Duisburg | 0:4 |
Tunisia