| 1. Round | 14/08/2021 | Chemnitzer FC [Youth B] | - | Erzgebirge Aue [Youth B] | 2:0 | ||||
| 2. Round | 21/08/2021 | Erzgebirge Aue [Youth B] | - | FC Carl Zeiss Jena [Youth B] | 1:0 | ||||
| 3. Round | 28/08/2021 | Hallescher FC [Youth B] | - | Erzgebirge Aue [Youth B] | 2:2 |  |
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| 4. Round | 11/09/2021 | Erzgebirge Aue [Youth B] | - | 1. FC Union Berlin [Youth B] | 1:0 | ||||
| 6. Round | 25/09/2021 | Erzgebirge Aue [Youth B] | - | Dynamo Dresden [Youth B] | 0:2 | ||||
| 7. Round | 02/10/2021 | FC Viktoria 1889 Berlin [Youth B] | - | Erzgebirge Aue [Youth B] | 1:0 | ||||
| 9. Round | 30/10/2021 | Erzgebirge Aue [Youth B] | - | RB Leipzig [Youth B] | 1:1 | ||||
| 10. Round | 06/11/2021 | FC St. Pauli [Youth B] | - | Erzgebirge Aue [Youth B] | 5:0 | ||||
| 17. Round | 02/04/2022 | Erzgebirge Aue [Youth B] | - | Hamburger SV [Youth B] | 1:1 | ||||
| 18. Round | 09/04/2022 | Hertha Zehlendorf [Youth B] | - | Erzgebirge Aue [Youth B] | 1:0 | ||||
| 19. Round | 23/04/2022 | Erzgebirge Aue [Youth B] | - | Hansa Rostock [Youth B] | 1:0 |
Germany