| 2. Round | 05/08/2017 | TSV Schott Mainz | - | 1899 Hoffenheim II | 1:3 | ||||
| 4. Round | 18/08/2017 | 1899 Hoffenheim II | - | TSV Steinbach | 1:3 | ||||
| 25. Round | 07/03/2018 | Hessen Kassel | - | 1899 Hoffenheim II | 2:1 | ||||
| 28. Round | 10/03/2018 | 1899 Hoffenheim II | - | SC Freiburg II | 0:1 | ||||
| 23. Round | 13/03/2018 | TSV Steinbach | - | 1899 Hoffenheim II | 0:2 | ||||
| 29. Round | 17/03/2018 | Stuttgarter Kickers | - | 1899 Hoffenheim II | 2:2 |  |
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| 30. Round | 23/03/2018 | 1899 Hoffenheim II | - | 1. FSV Mainz 05 II | 2:0 | ||||
| 31. Round | 27/03/2018 | FSV Frankfurt | - | 1899 Hoffenheim II | 2:0 | ||||
| 32. Round | 01/04/2018 | 1899 Hoffenheim II | - | Wormatia Worms | 2:2 | ||||
| 33. Round | 06/04/2018 | FC-Astoria Walldorf | - | 1899 Hoffenheim II | 0:2 | ||||
| 27. Round | 11/04/2018 | SV Röchling Völklingen | - | 1899 Hoffenheim II | 1:2 | ||||
| 35. Round | 21/04/2018 | Eintracht Stadtallendorf | - | 1899 Hoffenheim II | 3:1 | ||||
| 36. Round | 28/04/2018 | 1899 Hoffenheim II | - | Waldhof Mannheim | 2:2 | ||||
| 37. Round | 05/05/2018 | 1. FC Saarbrücken | - | 1899 Hoffenheim II | 1:1 | ||||
| 38. Round | 12/05/2018 | 1899 Hoffenheim II | - | VfB Stuttgart II | 3:0 |
Germany