| 1. Round | 14/08/2021 | FV Eppelborn | - | TSG Pfeddersheim | 3:6 | ||||
| 3. Round | 25/08/2021 | FV Eppelborn | - | FSV Jägersburg | 1:4 | ||||
| 4. Round | 28/08/2021 | FV 07 Diefflen | - | FV Eppelborn | 2:0 | ||||
| 5. Round | 04/09/2021 | FV Eppelborn | - | FC Hertha Wiesbach | 1:3 | ||||
| 6. Round | 11/09/2021 | Wormatia Worms | - | FV Eppelborn | 2:0 | ||||
| 7. Round | 18/09/2021 | FV Eppelborn | - | Arminia Ludwigshafen | 0:1 | ||||
| 9. Round | 25/09/2021 | FV Eppelborn | - | SV Röchling Völklingen | 4:1 | ||||
| 10. Round | 02/10/2021 | FV Eppelborn | - | FC Speyer 09 | 2:1 | ||||
| 11. Round | 09/10/2021 | TuS Mechtersheim | - | FV Eppelborn | 4:1 | ||||
| 22. Round | 05/03/2022 | FV Eppelborn | - | TuS Mechtersheim | 3:3 |  |
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| 16. Round | 09/03/2022 | FC Hertha Wiesbach | - | FV Eppelborn | 6:0 |
Germany