| 4. Round | 05/09/2021 | TuS Bersenbrück | - | Heeslinger SC | 1:1 | ||||
| 5. Round | 12/09/2021 | TuS Bersenbrück | - | VfL Oldenburg | 0:2 | ||||
| 6. Round | 19/09/2021 | Rotenburger SV | - | TuS Bersenbrück | 1:1 | ||||
| 7. Round | 26/09/2021 | TuS Bersenbrück | - | Kickers Emden | 2:1 | ||||
| 8. Round | 03/10/2021 | FC Hagen/Uthlede | - | TuS Bersenbrück | 1:0 | ||||
| 9. Round | 10/10/2021 | TuS Bersenbrück | - | SC Spelle-Venhaus | 3:0 | ||||
| 10. Round | 17/10/2021 | TuS Bersenbrück | - | Blau-Weiß Lohne | 2:0 | ||||
| 11. Round | 24/10/2021 | MTV Eintracht Celle | - | TuS Bersenbrück | 5:3 |  |
Germany