| 1. Round | 13/08/2021 | FV Engers 07 | - | TuS Koblenz | 1:1 | ||||
| 2. Round | 21/08/2021 | TuS Koblenz | - | SG Mülheim-Kärlich | 2:0 | ||||
| 3. Round | 24/08/2021 | TSV Emmelshausen | - | TuS Koblenz | 0:2 | ||||
| 4. Round | 28/08/2021 | SV Alemannia Waldalgesheim | - | TuS Koblenz | 3:1 | ||||
| 5. Round | 05/09/2021 | TuS Koblenz | - | Eintracht Trier | 0:2 | ||||
| 6. Round | 11/09/2021 | TuS Koblenz | - | Hassia Bingen | 1:2 | ||||
| 7. Round | 18/09/2021 | Sportfreunde Eisbachtal | - | TuS Koblenz | 2:2 | ||||
| 8. Round | 22/09/2021 | TuS Koblenz | - | SV Gonsenheim | 1:2 | ||||
| 20. Round | 27/11/2021 | TuS Koblenz | - | FC Karbach | 0:2 | ||||
| 21. Round | 20/02/2022 | FSV Salmrohr | - | TuS Koblenz | 1:0 |
Germany