| 2. Round | 20/08/2022 | FC Schalke 04 [Youth B] | - | SC Paderborn 07 [Youth B] | 5:0 | ||||
| 3. Round | 28/08/2022 | SC Paderborn 07 [Youth B] | - | Bor. Mönchengladbach [Youth B] | 2:2 | ||||
| 4. Round | 03/09/2022 | Preußen Münster [Youth B] | - | SC Paderborn 07 [Youth B] | 2:2 |  |
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| 5. Round | 11/09/2022 | 1. FC Köln [Youth B] | - | SC Paderborn 07 [Youth B] | 5:1 | |
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| 6. Round | 18/09/2022 | SC Paderborn 07 [Youth B] | - | Rot-Weiss Essen [Youth B] | 2:2 | ||||
| 7. Round | 01/10/2022 | FC Hennef 05 [Youth B] | - | SC Paderborn 07 [Youth B] | 0:2 | ||||
| 9. Round | 30/10/2022 | SV Deutz 05 [Youth B] | - | SC Paderborn 07 [Youth B] | 1:2 | ||||
| 10. Round | 05/11/2022 | SC Paderborn 07 [Youth B] | - | VfL Bochum [Youth B] | 1:1 | ||||
| 11. Round | 12/11/2022 | MSV Duisburg [Youth B] | - | SC Paderborn 07 [Youth B] | 1:0 |
Germany