| 1. Round | 13/09/2020 | FC Groningen | - | PSV Eindhoven | 1:3 | ||||
| 4. Round | 04/10/2020 | PSV Eindhoven | - | Fortuna Sittard | 2:0 | ||||
| 5. Round | 18/10/2020 | PEC Zwolle | - | PSV Eindhoven | 0:3 | ||||
| 6. Round | 25/10/2020 | Vitesse | - | PSV Eindhoven | 2:1 | ||||
| 10. Round | 29/11/2020 | PSV Eindhoven | - | Sparta Rotterdam | 1:0 | ||||
| 11. Round | 06/12/2020 | sc Heerenveen | - | PSV Eindhoven | 2:2 | ||||
| 12. Round | 13/12/2020 | PSV Eindhoven | - | FC Utrecht | 2:1 | ||||
| 13. Round | 19/12/2020 | RKC Waalwijk | - | PSV Eindhoven | 1:4 | ||||
| 14. Round | 22/12/2020 | PSV Eindhoven | - | VVV-Venlo | 4:1 |
Netherlands