| 21. Round | 06/02/2022 | Feyenoord | - | Sparta Rotterdam | 4:0 | ||||
| 22. Round | 13/02/2022 | RKC Waalwijk | - | Feyenoord | 0:2 |  |
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| 23. Round | 20/02/2022 | Feyenoord | - | SC Cambuur | 3:1 | ||||
| 24. Round | 27/02/2022 | AZ Alkmaar | - | Feyenoord | 2:1 |  |
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| 27. Round | 20/03/2022 | AFC Ajax | - | Feyenoord | 3:2 | ||||
| 29. Round | 10/04/2022 | Heracles Almelo | - | Feyenoord | 1:4 | ||||
| 31. Round | 01/05/2022 | Fortuna Sittard | - | Feyenoord | 1:3 | ||||
| 33. Round | 11/05/2022 | Go Ahead Eagles | - | Feyenoord | 0:1 | ||||
| 34. Round | 15/05/2022 | Feyenoord | - | FC Twente | 1:2 |
Netherlands