| 18. Round | 20/02/2022 | BC Viktoria Glesch-Paffendorf | - | VfL 08 Vichttal | 2:1 | ||||
| 21. Round | 13/03/2022 | VfL 08 Vichttal | - | Blau-Weiß Friesdorf | 3:2 |  |
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| 20. Round | 17/03/2022 | VfL 08 Vichttal | - | FC Pesch 1956 | 3:3 | |
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| 22. Round | 20/03/2022 | VfL Alfter | - | VfL 08 Vichttal | 1:0 | ||||
| 24. Round | 02/04/2022 | SV Deutz 05 | - | VfL 08 Vichttal | 0:2 | ||||
| 25. Round | 10/04/2022 | VfL 08 Vichttal | - | SV 1914 Eilendorf | 2:2 | ||||
| 23. Round | 14/04/2022 | VfL 08 Vichttal | - | SV Bergisch Gladbach 09 | 1:3 | ||||
| 26. Round | 18/04/2022 | 1. FC Düren | - | VfL 08 Vichttal | 6:0 | ||||
| 27. Round | 24/04/2022 | VfL 08 Vichttal | - | Viktoria Arnoldsweiler | 2:0 | |
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| 28. Round | 01/05/2022 | Fortuna Köln II | - | VfL 08 Vichttal | 6:1 | |
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| 29. Round | 08/05/2022 | VfL 08 Vichttal | - | Siegburger SV 04 | 2:1 | ||||
| 30. Round | 15/05/2022 | FC Hennef 05 | - | VfL 08 Vichttal | 5:1 | ||||
| 31. Round | 22/05/2022 | VfL 08 Vichttal | - | Spvg Wesseling-Urfeld | 5:2 | |
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| 32. Round | 29/05/2022 | FC Hürth | - | VfL 08 Vichttal | 2:1 | |
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| 33. Round | 06/06/2022 | SV Breinig | - | VfL 08 Vichttal | 3:2 | |
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| 34. Round | 12/06/2022 | VfL 08 Vichttal | - | SpVg Frechen 20 | 0:4 |
Germany