| 14. Round | 17/02/1978 | HFC Chemie | - | BFC Dynamo | 0:0 | ||||
| 15. Round | 23/02/1978 | FC Carl Zeiss Jena | - | HFC Chemie | 6:1 | ||||
| 16. Round | 03/03/1978 | HFC Chemie | - | Dynamo Dresden | 0:0 | ||||
| 17. Round | 17/03/1978 | BSG Wismut Aue | - | HFC Chemie | 0:1 | ||||
| 18. Round | 01/04/1978 | HFC Chemie | - | BSG Sachsenring Zwickau | 2:0 | ||||
| 19. Round | 08/04/1978 | HFC Chemie | - | FC Vorwärts Frankfurt/Oder | 2:2 |  |
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| 20. Round | 14/04/1978 | 1. FC Lokomotive Leipzig | - | HFC Chemie | 2:0 | ||||
| 21. Round | 22/04/1978 | HFC Chemie | - | 1. FC Union Berlin | 1:2 | ||||
| 22. Round | 06/05/1978 | Rot-Weiß Erfurt | - | HFC Chemie | 1:1 | ||||
| 23. Round | 11/05/1978 | HFC Chemie | - | FC Karl-Marx-Stadt | 3:1 | ||||
| 24. Round | 20/05/1978 | BSG Wismut Gera | - | HFC Chemie | 0:1 | ||||
| 25. Round | 26/05/1978 | HFC Chemie | - | 1. FC Magdeburg | 2:1 | |
Germany