| 1. Round | 12/09/2021 | Arminia Bielefeld [Youth] | - | Fortuna Düsseldorf [Youth] | 1:2 |  |
|||
| 2. Round | 18/09/2021 | Alemannia Aachen [Youth] | - | Arminia Bielefeld [Youth] | 0:1 | ||||
| 3. Round | 25/09/2021 | Arminia Bielefeld [Youth] | - | Bayer Leverkusen [Youth] | 0:4 | ||||
| 4. Round | 02/10/2021 | Wuppertaler SV [Youth] | - | Arminia Bielefeld [Youth] | 0:1 | ||||
| 5. Round | 16/10/2021 | Arminia Bielefeld [Youth] | - | Borussia Dortmund [Youth] | 1:2 | ||||
| 7. Round | 30/10/2021 | Arminia Bielefeld [Youth] | - | Bor. Mönchengladbach [Youth] | 1:1 | |
|||
| 6. Round | 07/11/2021 | Viktoria Köln [Youth] | - | Arminia Bielefeld [Youth] | 2:0 | |
|||
| 8. Round | 27/11/2021 | VfL Bochum [Youth] | - | Arminia Bielefeld [Youth] | 0:0 | ||||
| 9. Round | 05/12/2021 | Arminia Bielefeld [Youth] | - | Preußen Münster [Youth] | 0:1 | ||||
| 10. Round | 06/02/2022 | Rot-Weiss Essen [Youth] | - | Arminia Bielefeld [Youth] | 0:0 | ||||
| 11. Round | 12/02/2022 | Arminia Bielefeld [Youth] | - | Rot-Weiß Oberhausen [Youth] | 2:3 | |
|||
| 12. Round | 19/02/2022 | SC Paderborn 07 [Youth] | - | Arminia Bielefeld [Youth] | 3:2 | ||||
| 16. Round | 23/04/2022 | Arminia Bielefeld [Youth] | - | FC Schalke 04 [Youth] | 0:3 | |
Germany