| 1. Round | 07/08/2021 | VfB 1921 Krieschow | - | FSV Martinroda | 3:2 |  |
|||
| 2. Round | 14/08/2021 | FSV Martinroda | - | VFC Plauen | 0:2 | ||||
| 3. Round | 18/08/2021 | Rot-Weiß Erfurt | - | FSV Martinroda | 3:0 | ||||
| 4. Round | 22/08/2021 | FSV Martinroda | - | FC Grimma | 1:2 | ||||
| 5. Round | 28/08/2021 | Union Sandersdorf | - | FSV Martinroda | 0:0 | ||||
| 6. Round | 11/09/2021 | FSV Martinroda | - | FSV Budissa Bautzen | 2:4 | ||||
| 7. Round | 18/09/2021 | FSV Martinroda | - | Blau-Weiß Zorbau | 3:1 | ||||
| 8. Round | 25/09/2021 | Bischofswerdaer FV | - | FSV Martinroda | 2:1 | ||||
| 9. Round | 29/09/2021 | FSV Martinroda | - | FC Einheit Rudolstadt | 0:2 | ||||
| 14. Round | 05/02/2022 | FC Oberlausitz | - | FSV Martinroda | 3:2 | ||||
| 18. Round | 06/03/2022 | Einheit Wernigerode | - | FSV Martinroda | 4:0 |
Syria