| 1. Round | 04/08/1980 | Waldhof Mannheim | - | Freiburger FC | 5:0 | ||||
| 2. Round | 08/08/1980 | Freiburger FC | - | SSV Ulm 1846 | 0:1 | ||||
| 7. Round | 04/09/1980 | Wormatia Worms | - | Freiburger FC | 1:3 | ||||
| 9. Round | 19/09/1980 | SV Darmstadt 98 | - | Freiburger FC | 6:3 | ||||
| 10. Round | 25/09/1980 | Freiburger FC | - | SC Freiburg | 1:2 |  |
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| 15. Round | 07/11/1980 | Borussia Neunkirchen | - | Freiburger FC | 0:3 | ||||
| 16. Round | 14/11/1980 | Freiburger FC | - | VfR Bürstadt | 3:2 | |
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| 17. Round | 27/11/1980 | Stuttgarter Kickers | - | Freiburger FC | 4:0 |  |
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| 19. Round | 12/12/1980 | Kickers Offenbach | - | Freiburger FC | 4:2 | ||||
| 18. Round | 19/12/1980 | Freiburger FC | - | ESV Ingolstadt | 2:2 | ||||
| 31. Round | 03/04/1981 | FC Augsburg | - | Freiburger FC | 1:1 | ||||
| 35. Round | 29/04/1981 | VfR Bürstadt | - | Freiburger FC | 4:1 | ||||
| 37. Round | 14/05/1981 | ESV Ingolstadt | - | Freiburger FC | 4:3 | |
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| 38. Round | 29/05/1981 | Freiburger FC | - | Kickers Offenbach | 4:2 |
Germany