| 1. Round | 15/08/2021 | Union Tornesch | - | TuS Osdorf | 2:4 |  |
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| 2. Round | 20/08/2021 | TuS Osdorf | - | SV Rugenbergen | 2:1 | ||||
| 3. Round | 27/08/2021 | TuS Osdorf | - | FC Süderelbe | 1:3 | ||||
| 4. Round | 05/09/2021 | HEBC Hamburg | - | TuS Osdorf | 2:5 | ||||
| 5. Round | 17/09/2021 | TuS Osdorf | - | Niendorfer TSV | 2:1 | |
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| 7. Round | 01/10/2021 | TuS Osdorf | - | Hamburger SV III | 9:1 | |
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| 8. Round | 08/10/2021 | Victoria Hamburg | - | TuS Osdorf | 2:2 | ||||
| 9. Round | 15/10/2021 | TuS Osdorf | - | TSV Buchholz 08 | 1:2 | |
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| 10. Round | 22/10/2021 | TuS Osdorf | - | Union Tornesch | 3:2 | ||||
| 11. Round | 31/10/2021 | SV Rugenbergen | - | TuS Osdorf | 4:0 | ||||
| 12. Round | 13/11/2021 | FC Süderelbe | - | TuS Osdorf | 2:0 | ||||
| 13. Round | 19/11/2021 | TuS Osdorf | - | HEBC Hamburg | 2:3 | ||||
| 14. Round | 28/11/2021 | Niendorfer TSV | - | TuS Osdorf | 1:0 | ||||
| 17. Round | 28/01/2022 | TuS Osdorf | - | Victoria Hamburg | 3:1 | |
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| 18. Round | 03/03/2022 | TSV Buchholz 08 | - | TuS Osdorf | 2:2 |
Germany