| 2. Round | 21/08/2021 | FSV Salmrohr | - | TSV Emmelshausen | 1:2 | ||||
| 4. Round | 28/08/2021 | FSV Salmrohr | - | Eintracht Trier | 1:4 | ||||
| 5. Round | 04/09/2021 | Hassia Bingen | - | FSV Salmrohr | 1:2 | ||||
| 6. Round | 12/09/2021 | FSV Salmrohr | - | Sportfreunde Eisbachtal | 2:5 | ||||
| 7. Round | 19/09/2021 | SV Gonsenheim | - | FSV Salmrohr | 0:2 | ||||
| 8. Round | 22/09/2021 | FSV Salmrohr | - | FC Karbach | 0:2 | ||||
| 9. Round | 26/09/2021 | 1. FC Kaiserslautern II | - | FSV Salmrohr | 3:1 | ||||
| 10. Round | 03/10/2021 | TuS Koblenz | - | FSV Salmrohr | 5:2 | ||||
| 13. Round | 23/10/2021 | TSV Emmelshausen | - | FSV Salmrohr | 3:0 | ||||
| 16. Round | 06/11/2021 | FSV Salmrohr | - | Hassia Bingen | 3:3 | ||||
| 17. Round | 13/11/2021 | Sportfreunde Eisbachtal | - | FSV Salmrohr | 4:0 | ||||
| 19. Round | 24/11/2021 | FC Karbach | - | FSV Salmrohr | 1:4 | ||||
| 20. Round | 27/11/2021 | FSV Salmrohr | - | 1. FC Kaiserslautern II | 3:1 |
Germany