| 6. Round | 11/09/2021 | Rostocker FC | - | Hansa Rostock II | 3:1 | ||||
| 3. Round | 15/09/2021 | Greifswalder FC | - | Hansa Rostock II | 1:1 | ||||
| 9. Round | 02/10/2021 | Blau-Weiß 90 Berlin | - | Hansa Rostock II | 2:0 | ||||
| 10. Round | 16/10/2021 | Hansa Rostock II | - | MSV Pampow | 4:0 | ||||
| 14. Round | 13/11/2021 | Hansa Rostock II | - | RSV Eintracht 1949 | 2:2 | ||||
| 17. Round | 20/02/2022 | Hertha Zehlendorf | - | Hansa Rostock II | 2:0 | ||||
| 19. Round | 05/03/2022 | FC Mecklenburg Schwerin | - | Hansa Rostock II | 0:3 | ||||
| 22. Round | 01/04/2022 | Hansa Rostock II | - | Greifswalder FC | 1:2 | ||||
| 26. Round | 01/05/2022 | Hansa Rostock II | - | Torgelower FC Greif | 1:1 |
Germany