| 1. Round | 14/08/2021 | Wormatia Worms | - | FC Hertha Wiesbach | 0:1 | ||||
| 2. Round | 21/08/2021 | FC Hertha Wiesbach | - | Arminia Ludwigshafen | 2:2 | ||||
| 3. Round | 25/08/2021 | SV 07 Elversberg II | - | FC Hertha Wiesbach | 2:4 | ||||
| 4. Round | 28/08/2021 | FC Hertha Wiesbach | - | SV Röchling Völklingen | 2:1 | ||||
| 5. Round | 04/09/2021 | FV Eppelborn | - | FC Hertha Wiesbach | 1:3 |  |
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| 6. Round | 11/09/2021 | FC Hertha Wiesbach | - | TuS Mechtersheim | 3:2 | ||||
| 13. Round | 23/10/2021 | Arminia Ludwigshafen | - | FC Hertha Wiesbach | 3:3 | ||||
| 14. Round | 27/10/2021 | FC Hertha Wiesbach | - | SV 07 Elversberg II | 5:1 | ||||
| 15. Round | 31/10/2021 | SV Röchling Völklingen | - | FC Hertha Wiesbach | 0:1 | ||||
| 17. Round | 13/11/2021 | TuS Mechtersheim | - | FC Hertha Wiesbach | 2:2 | ||||
| 18. Round | 20/11/2021 | FC Hertha Wiesbach | - | TSG Pfeddersheim | 3:2 | ||||
| 20. Round | 27/11/2021 | FC Hertha Wiesbach | - | FSV Jägersburg | 4:1 | ||||
| 19. Round | 23/02/2022 | FV Dudenhofen | - | FC Hertha Wiesbach | 1:4 | ||||
| 21. Round | 26/02/2022 | FV 07 Diefflen | - | FC Hertha Wiesbach | 2:0 | ||||
| 22. Round | 05/03/2022 | FC Hertha Wiesbach | - | FC Speyer 09 | 8:1 |
Germany