| 1. Round | 20/08/2010 | Alemannia Aachen | - | 1. FC Union Berlin | 2:2 | ||||
| 2. Round | 28/08/2010 | 1. FC Union Berlin | - | SpVgg Greuther Fürth | 1:2 |  |
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| 6. Round | 26/09/2010 | 1. FC Union Berlin | - | MSV Duisburg | 2:0 | ||||
| 9. Round | 22/10/2010 | FC Augsburg | - | 1. FC Union Berlin | 2:1 | ||||
| 14. Round | 28/11/2010 | FC Ingolstadt 04 | - | 1. FC Union Berlin | 1:0 | ||||
| 15. Round | 06/12/2010 | 1. FC Union Berlin | - | VfL Bochum | 0:1 | ||||
| 16. Round | 13/12/2010 | Energie Cottbus | - | 1. FC Union Berlin | 0:0 | ||||
| 17. Round | 20/12/2010 | 1. FC Union Berlin | - | Karlsruher SC | 3:1 | ||||
| 18. Round | 14/01/2011 | 1. FC Union Berlin | - | Alemannia Aachen | 2:1 | ||||
| 19. Round | 23/01/2011 | SpVgg Greuther Fürth | - | 1. FC Union Berlin | 1:0 | |
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| 20. Round | 30/01/2011 | 1. FC Union Berlin | - | SC Paderborn 07 | 0:2 | ||||
| 28. Round | 03/04/2011 | Rot-Weiß Oberhausen | - | 1. FC Union Berlin | 0:2 | ||||
| 33. Round | 08/05/2011 | 1. FC Union Berlin | - | Energie Cottbus | 4:2 | ||||
| 34. Round | 15/05/2011 | Karlsruher SC | - | 1. FC Union Berlin | 3:2 |
Congo