| 1. Round | 14/08/2022 | VfL Bochum [Youth B] | - | MSV Duisburg [Youth B] | 3:1 | ||||
| 2. Round | 20/08/2022 | MSV Duisburg [Youth B] | - | 1. FC Köln [Youth B] | 2:1 | ||||
| 3. Round | 27/08/2022 | MSV Duisburg [Youth B] | - | Borussia Dortmund [Youth B] | 0:3 | ||||
| 6. Round | 17/09/2022 | Fortuna Köln [Youth B] | - | MSV Duisburg [Youth B] | 1:4 | ||||
| 7. Round | 01/10/2022 | MSV Duisburg [Youth B] | - | Arminia Bielefeld [Youth B] | 2:6 | ||||
| 8. Round | 08/10/2022 | FC Schalke 04 [Youth B] | - | MSV Duisburg [Youth B] | 2:0 | ||||
| 4. Round | 22/10/2022 | Sportfreunde Siegen [Youth B] | - | MSV Duisburg [Youth B] | 1:2 |  |
|||
| 9. Round | 29/10/2022 | MSV Duisburg [Youth B] | - | Bor. Mönchengladbach [Youth B] | 1:3 |  |
|
||
| 10. Round | 05/11/2022 | Preußen Münster [Youth B] | - | MSV Duisburg [Youth B] | 1:1 | |
 |
||
| 12. Round | 19/11/2022 | Rot-Weiss Essen [Youth B] | - | MSV Duisburg [Youth B] | 2:0 | |
|||
| 13. Round | 26/02/2023 | MSV Duisburg [Youth B] | - | FC Hennef 05 [Youth B] | 1:1 | |
|||
| 14. Round | 04/03/2023 | Bayer Leverkusen [Youth B] | - | MSV Duisburg [Youth B] | 1:0 | |
Germany