| 2. Round | 06/09/1980 | BSG Schiffahrt/Hafen Rostock | - | BSG Lok Anklam | 6:2 | ||||
| 5. Round | 04/10/1980 | BSG Lok Anklam | - | TSG Wismar | 1:1 | ||||
| 8. Round | 26/10/1980 | SG Dynamo Schwerin | - | BSG Lok Anklam | 9:2 | ||||
| 10. Round | 15/11/1980 | Chemie/Motor Veritas Wittenberge | - | BSG Lok Anklam | 0:1 | ||||
| 12. Round | 29/11/1980 | ASG Vorwärts Stralsund | - | BSG Lok Anklam | 6:0 | ||||
| 14. Round | 12/12/1980 | ISG Schwerin | - | BSG Lok Anklam | 4:0 | ||||
| 16. Round | 07/03/1981 | TSG Wismar | - | BSG Lok Anklam | 2:0 | ||||
| 17. Round | 14/03/1981 | BSG Lok Anklam | - | BSG Motor Wolgast | 2:1 | ||||
| 18. Round | 21/03/1981 | TSG Bau Rostock | - | BSG Lok Anklam | 0:0 | ||||
| 19. Round | 28/03/1981 | BSG Lok Anklam | - | SG Dynamo Schwerin | 1:2 | ||||
| 20. Round | 03/04/1981 | BSG Post Neubrandenburg | - | BSG Lok Anklam | 2:2 | ||||
| 22. Round | 16/04/1981 | BSG KKW Greifswald | - | BSG Lok Anklam | 0:2 | ||||
| 21. Round | 24/04/1981 | BSG Lok Anklam | - | Chemie/Motor Veritas Wittenberge | 3:1 |
Germany