| 25. Round | 05/02/2022 | FSV Zwickau | - | 1. FC Kaiserslautern | 0:2 | ||||
| 26. Round | 11/02/2022 | Hallescher FC | - | FSV Zwickau | 2:0 | ||||
| 29. Round | 05/03/2022 | SC Freiburg II | - | FSV Zwickau | 1:0 | ||||
| 30. Round | 13/03/2022 | FSV Zwickau | - | VfL Osnabrück | 1:3 | ||||
| 24. Round | 16/03/2022 | FC Viktoria 1889 Berlin | - | FSV Zwickau | 0:0 | ||||
| 31. Round | 20/03/2022 | MSV Duisburg | - | FSV Zwickau | 0:1 | ||||
| 33. Round | 10/04/2022 | TSV Havelse | - | FSV Zwickau | 0:3 |  |
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| 34. Round | 16/04/2022 | FSV Zwickau | - | SV Wehen Wiesbaden | 2:1 | |
Germany