| 1. Round | 24/07/2021 | Berliner AK 07 | - | FC Carl Zeiss Jena | 1:0 | ||||
| 2. Round | 27/07/2021 | FC Carl Zeiss Jena | - | VSG Altglienicke | 1:2 | ||||
| 3. Round | 31/07/2021 | 1. FC Lok Leipzig | - | FC Carl Zeiss Jena | 0:0 | ||||
| 5. Round | 13/08/2021 | FC Eilenburg | - | FC Carl Zeiss Jena | 1:3 | ||||
| 7. Round | 21/08/2021 | ZFC Meuselwitz | - | FC Carl Zeiss Jena | 1:3 | ||||
| 17. Round | 24/11/2021 | FC Carl Zeiss Jena | - | VfB Auerbach | 2:1 | ||||
| 19. Round | 28/11/2021 | FC Carl Zeiss Jena | - | Union Fürstenwalde | 4:1 | ||||
| 24. Round | 04/02/2022 | FC Carl Zeiss Jena | - | FC Eilenburg | 3:1 | ||||
| 37. Round | 07/05/2022 | FC Carl Zeiss Jena | - | TeBe Berlin | 2:1 | ||||
| 38. Round | 15/05/2022 | Union Fürstenwalde | - | FC Carl Zeiss Jena | 1:0 |
Germany