| 1. Round | 12/09/2021 | Arminia Bielefeld [Youth] | - | Fortuna Düsseldorf [Youth] | 1:2 | ||||
| 2. Round | 19/09/2021 | Fortuna Düsseldorf [Youth] | - | FC Schalke 04 [Youth] | 0:1 | ||||
| 3. Round | 26/09/2021 | 1. FC Köln [Youth] | - | Fortuna Düsseldorf [Youth] | 6:1 | ||||
| 5. Round | 17/10/2021 | Fortuna Düsseldorf [Youth] | - | Alemannia Aachen [Youth] | 2:1 | ||||
| 6. Round | 23/10/2021 | Bayer Leverkusen [Youth] | - | Fortuna Düsseldorf [Youth] | 3:1 | ||||
| 7. Round | 30/10/2021 | Fortuna Düsseldorf [Youth] | - | Wuppertaler SV [Youth] | 0:2 | ||||
| 8. Round | 28/11/2021 | Borussia Dortmund [Youth] | - | Fortuna Düsseldorf [Youth] | 9:1 | ||||
| 9. Round | 30/01/2022 | Fortuna Düsseldorf [Youth] | - | Viktoria Köln [Youth] | 1:2 | ||||
| 10. Round | 06/02/2022 | Bor. Mönchengladbach [Youth] | - | Fortuna Düsseldorf [Youth] | 1:2 | ||||
| 12. Round | 20/02/2022 | Preußen Münster [Youth] | - | Fortuna Düsseldorf [Youth] | 1:3 | ||||
| 13. Round | 06/03/2022 | Fortuna Düsseldorf [Youth] | - | Rot-Weiss Essen [Youth] | 1:1 | ||||
| 11. Round | 12/03/2022 | Fortuna Düsseldorf [Youth] | - | VfL Bochum [Youth] | 0:2 |
Germany