| 1. Round | 22/08/2021 | TV Jahn Hiesfeld | - | FC Kray | 1:4 | ||||
| 2. Round | 29/08/2021 | FC Kray | - | SpVg Schonnebeck | 2:5 | ||||
| 3. Round | 05/09/2021 | Cronenberger SC | - | FC Kray | 2:2 | ||||
| 4. Round | 12/09/2021 | FC Kray | - | SC Union Nettetal | 3:2 | ||||
| 5. Round | 19/09/2021 | SC Düsseldorf-West | - | FC Kray | 1:0 | ||||
| 7. Round | 03/10/2021 | 1. FC Kleve | - | FC Kray | 4:4 | ||||
| 8. Round | 10/10/2021 | FC Kray | - | TSV Meerbusch | 0:4 | ||||
| 9. Round | 17/10/2021 | 1. FC Bocholt | - | FC Kray | 3:0 | ||||
| 10. Round | 24/10/2021 | FC Kray | - | SSVg Velbert | 0:3 | ||||
| 11. Round | 31/10/2021 | TVD Velbert | - | FC Kray | 0:1 | ||||
| 12. Round | 07/11/2021 | FC Kray | - | SpVgg Sterkrade-Nord | 2:1 | ||||
| 6. Round | 10/11/2021 | FC Kray | - | Sportfreunde Baumberg | 0:3 | ||||
| 13. Round | 14/11/2021 | Schwarz-Weiß Essen | - | FC Kray | 1:1 | ||||
| 15. Round | 05/12/2021 | FC Kray | - | DJK Teutonia St. Tönis | 2:3 | ||||
| 16. Round | 12/12/2021 | TuRU Düsseldorf | - | FC Kray | 2:0 | ||||
| 17. Round | 18/12/2021 | FC Kray | - | Germania Ratingen 04/19 | 1:4 |
Germany