| 4. Round | 24/04/2022 | TuS Ennepetal | - | RSV Meinerzhagen | 2:0 | ||||
| 2. Round | 28/04/2022 | TuS Ennepetal | - | SpVgg Vreden | 2:2 | ||||
| 5. Round | 01/05/2022 | Holzwickeder SC | - | TuS Ennepetal | 4:2 |  |
|||
| 6. Round | 05/05/2022 | TuS Ennepetal | - | TSG Sprockhövel | 1:1 | |
 |
||
| 7. Round | 08/05/2022 | TuS Ennepetal | - | Hammer SpVg | 2:0 | ||||
| 9. Round | 20/05/2022 | Westfalia Herne | - | TuS Ennepetal | 1:3 | ||||
| 1. Round | 02/06/2022 | SG Finnentrop/Bamenohl | - | TuS Ennepetal | 4:2 | |
|||
| 11. Round | 06/06/2022 | TuS Ennepetal | - | Preußen Münster II | 1:3 |
Germany