| 8. Round | 17/10/2021 | Eintracht Frankfurt [Youth B] | - | 1. FC Nürnberg [Youth B] | 0:2 | ||||
| 12. Round | 27/11/2021 | TSV 1860 München [Youth B] | - | 1. FC Nürnberg [Youth B] | 1:0 | ||||
| 13. Round | 12/02/2022 | 1. FC Nürnberg [Youth B] | - | 1899 Hoffenheim [Youth B] | 1:3 | ||||
| 19. Round | 06/04/2022 | 1. FC Nürnberg [Youth B] | - | SpVgg Unterhaching [Youth B] | 2:0 | ||||
| 20. Round | 09/04/2022 | FSV Frankfurt [Youth B] | - | 1. FC Nürnberg [Youth B] | 0:3 |  |
Hungary