| 1. Round | 03/04/2022 | TV Jahn Hiesfeld | - | SC Düsseldorf-West | 2:2 |  |
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| 2. Round | 10/04/2022 | SC Düsseldorf-West | - | SC Union Nettetal | 4:0 | ||||
| 3. Round | 14/04/2022 | SpVgg Sterkrade-Nord | - | SC Düsseldorf-West | 0:3 | |
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| 4. Round | 24/04/2022 | SC Velbert | - | SC Düsseldorf-West | 0:0 | ||||
| 5. Round | 30/04/2022 | TuRU Düsseldorf | - | SC Düsseldorf-West | 3:1 | ||||
| 6. Round | 08/05/2022 | Cronenberger SC | - | SC Düsseldorf-West | 4:1 | ||||
| 7. Round | 15/05/2022 | SC Düsseldorf-West | - | DJK Teutonia St. Tönis | 0:1 | ||||
| 9. Round | 29/05/2022 | SC Düsseldorf-West | - | Sportfreunde Niederwenigern | 3:0 | ||||
| 8. Round | 01/06/2022 | SC Düsseldorf-West | - | 1. FC Mönchengladbach | 4:3 |  |
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| 11. Round | 12/06/2022 | FSV Duisburg | - | SC Düsseldorf-West | 4:1 |
Germany