| 1. Round | 15/08/2021 | Heeslinger SC | - | Kickers Emden | 1:2 | ||||
| 18. Round | 18/08/2021 | Kickers Emden | - | Rotenburger SV | 2:1 |  |
|||
| 2. Round | 21/08/2021 | Kickers Emden | - | FC Hagen/Uthlede | 3:0 | ||||
| 3. Round | 28/08/2021 | Kickers Emden | - | SC Spelle-Venhaus | 1:1 | ||||
| 4. Round | 04/09/2021 | Kickers Emden | - | Blau-Weiß Lohne | 3:1 | ||||
| 5. Round | 12/09/2021 | MTV Eintracht Celle | - | Kickers Emden | 1:2 | ||||
| 6. Round | 18/09/2021 | Kickers Emden | - | TB Uphusen | 5:1 | ||||
| 7. Round | 26/09/2021 | TuS Bersenbrück | - | Kickers Emden | 2:1 | ||||
| 8. Round | 02/10/2021 | Kickers Emden | - | VfL Oldenburg | 5:2 | ||||
| 9. Round | 10/10/2021 | Rotenburger SV | - | Kickers Emden | 1:2 | ||||
| 17. Round | 05/12/2021 | VfL Oldenburg | - | Kickers Emden | 4:1 | ||||
| 16. Round | 11/12/2021 | Kickers Emden | - | TuS Bersenbrück | 2:0 |
Germany