| 10. Round | 16/02/2022 | SG Unterrath 12/24 [Youth B] | - | 1. FC Köln [Youth B] | 2:2 |  |
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| 9. Round | 23/02/2022 | 1. FC Köln [Youth B] | - | Wuppertaler SV [Youth B] | 3:1 | ||||
| 12. Round | 26/02/2022 | Borussia Dortmund [Youth B] | - | 1. FC Köln [Youth B] | 2:1 | ||||
| 13. Round | 05/03/2022 | 1. FC Köln [Youth B] | - | Fortuna Düsseldorf [Youth B] | 5:1 | ||||
| 11. Round | 09/03/2022 | 1. FC Köln [Youth B] | - | Bor. Mönchengladbach [Youth B] | 1:0 |  |
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| 14. Round | 12/03/2022 | Arminia Bielefeld [Youth B] | - | 1. FC Köln [Youth B] | 1:1 |
Germany
Togo