| 1. Round | 18/03/2022 | SG Mülheim-Kärlich | - | TSG Pfeddersheim | 0:4 | ||||
| 1. Round | 26/03/2022 | TSG Pfeddersheim | - | Hassia Bingen | 2:2 | ||||
| 2. Round | 03/04/2022 | 1. FC Kaiserslautern II | - | TSG Pfeddersheim | 1:1 | ||||
| 2. Round | 09/04/2022 | FSV Salmrohr | - | TSG Pfeddersheim | 1:2 | ||||
| 2. Round | 23/04/2022 | TSV Emmelshausen | - | TSG Pfeddersheim | 1:1 | ||||
| 2. Round | 29/04/2022 | TSG Pfeddersheim | - | SG Mülheim-Kärlich | 3:0 | ||||
| 3. Round | 04/05/2022 | TSG Pfeddersheim | - | Sportfreunde Eisbachtal | 3:0 |  |
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| 3. Round | 07/05/2022 | Hassia Bingen | - | TSG Pfeddersheim | 2:5 |
Germany