| 4. Round | 22/08/2015 | FC Schalke 04 II | - | Bor. Mönchengladbach II | 2:5 | ||||
| 5. Round | 26/08/2015 | FC Schalke 04 II | - | Rot-Weiß Oberhausen | 2:2 | ||||
| 9. Round | 19/09/2015 | FC Schalke 04 II | - | 1. FC Köln II | 1:1 | ||||
| 10. Round | 22/09/2015 | SV Rödinghausen | - | FC Schalke 04 II | 1:2 | ||||
| 12. Round | 04/10/2015 | TuS Erndtebrück | - | FC Schalke 04 II | 1:4 | ||||
| 14. Round | 24/10/2015 | FC Wegberg-Beeck | - | FC Schalke 04 II | 2:3 | ||||
| 7. Round | 28/10/2015 | FC Schalke 04 II | - | Borussia Dortmund II | 0:0 | ||||
| 15. Round | 31/10/2015 | FC Schalke 04 II | - | SSVg Velbert | 1:1 | ||||
| 16. Round | 08/11/2015 | Rot-Weiss Essen | - | FC Schalke 04 II | 2:0 |
Germany