| 1. Round | 14/08/2021 | SG Mülheim-Kärlich | - | FSV Salmrohr | 1:2 | ||||
| 2. Round | 21/08/2021 | FSV Salmrohr | - | TSV Emmelshausen | 1:2 | ||||
| 7. Round | 19/09/2021 | SV Gonsenheim | - | FSV Salmrohr | 0:2 | ||||
| 8. Round | 22/09/2021 | FSV Salmrohr | - | FC Karbach | 0:2 | ||||
| 9. Round | 26/09/2021 | 1. FC Kaiserslautern II | - | FSV Salmrohr | 3:1 |  |
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| 10. Round | 03/10/2021 | TuS Koblenz | - | FSV Salmrohr | 5:2 | ||||
| 11. Round | 09/10/2021 | FSV Salmrohr | - | FV Engers 07 | 1:2 | ||||
| 13. Round | 23/10/2021 | TSV Emmelshausen | - | FSV Salmrohr | 3:0 | ||||
| 14. Round | 27/10/2021 | FSV Salmrohr | - | SV Alemannia Waldalgesheim | 1:2 | |
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| 15. Round | 30/10/2021 | Eintracht Trier | - | FSV Salmrohr | 1:2 | ||||
| 16. Round | 06/11/2021 | FSV Salmrohr | - | Hassia Bingen | 3:3 | ||||
| 12. Round | 10/11/2021 | FSV Salmrohr | - | SG Mülheim-Kärlich | 0:1 | ||||
| 17. Round | 13/11/2021 | Sportfreunde Eisbachtal | - | FSV Salmrohr | 4:0 |  |
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| 19. Round | 24/11/2021 | FC Karbach | - | FSV Salmrohr | 1:4 |  |
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| 20. Round | 27/11/2021 | FSV Salmrohr | - | 1. FC Kaiserslautern II | 3:1 | ||||
| 22. Round | 05/03/2022 | FV Engers 07 | - | FSV Salmrohr | 1:1 |
Germany