| 1. Round | 15/08/2021 | VfL Wolfsburg II [Women] | - | RB Leipzig [Women] | 1:2 | ||||
| 3. Round | 05/09/2021 | FSV Gütersloh 2009 [Women] | - | VfL Wolfsburg II [Women] | 6:0 | ||||
| 5. Round | 26/09/2021 | Bayern München II [Women] | - | VfL Wolfsburg II [Women] | 4:1 | ||||
| 9. Round | 13/11/2021 | Borussia Bocholt [Women] | - | VfL Wolfsburg II [Women] | 1:1 | ||||
| 10. Round | 20/11/2021 | VfL Wolfsburg II [Women] | - | SV 07 Elversberg [Women] | 2:0 | ||||
| 11. Round | 05/12/2021 | FC Ingolstadt 04 [Women] | - | VfL Wolfsburg II [Women] | 2:0 | ||||
| 18. Round | 10/04/2022 | VfL Wolfsburg II [Women] | - | Bayern München II [Women] | 0:1 | ||||
| 20. Round | 17/04/2022 | VfL Wolfsburg II [Women] | - | SV Meppen [Women] | 0:0 | ||||
| 19. Round | 20/04/2022 | Eintracht Frankfurt II [Women] | - | VfL Wolfsburg II [Women] | 2:2 |
Germany