| 4. Round | 11/09/2021 | VfL Wolfsburg [Youth B] | - | Hertha Zehlendorf [Youth B] | 3:2 | ||||
| 5. Round | 18/09/2021 | Hansa Rostock [Youth B] | - | VfL Wolfsburg [Youth B] | 1:1 | ||||
| 6. Round | 25/09/2021 | VfL Wolfsburg [Youth B] | - | Chemnitzer FC [Youth B] | 2:0 | ||||
| 3. Round | 29/09/2021 | Hamburger SV [Youth B] | - | VfL Wolfsburg [Youth B] | 2:2 | ||||
| 7. Round | 02/10/2021 | FC Carl Zeiss Jena [Youth B] | - | VfL Wolfsburg [Youth B] | 1:1 | ||||
| 2. Round | 13/02/2022 | VfL Wolfsburg [Youth B] | - | Holstein Kiel [Youth B] | 4:2 | ||||
| 15. Round | 05/03/2022 | FC St. Pauli [Youth B] | - | VfL Wolfsburg [Youth B] | 1:1 | ||||
| 16. Round | 12/03/2022 | VfL Wolfsburg [Youth B] | - | Energie Cottbus [Youth B] | 5:0 | ||||
| 17. Round | 02/04/2022 | Hertha BSC [Youth B] | - | VfL Wolfsburg [Youth B] | 4:3 |
Germany