| 6. Round | 11/09/2021 | SC Waldgirmes | - | FC Eddersheim | 1:0 | ||||
| 7. Round | 15/09/2021 | SC Waldgirmes | - | FV Bad Vilbel | 3:1 | ||||
| 8. Round | 19/09/2021 | SV Zeilsheim | - | SC Waldgirmes | 1:5 |  |
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| 1. Round | 22/09/2021 | SC Waldgirmes | - | Türk Gücü Friedberg | 2:2 | ||||
| 14. Round | 23/10/2021 | Hessen Dreieich | - | SC Waldgirmes | 3:2 | ||||
| 15. Round | 27/10/2021 | SC Waldgirmes | - | Rot-Weiß Walldorf | 3:2 | ||||
| 16. Round | 30/10/2021 | SC Waldgirmes | - | Hessen Dreieich | 4:2 | ||||
| 18. Round | 13/11/2021 | TuS Dietkirchen | - | SC Waldgirmes | 2:2 | ||||
| 19. Round | 20/11/2021 | SC Waldgirmes | - | Viktoria Griesheim | 2:0 | ||||
| 21. Round | 04/12/2021 | SC Waldgirmes | - | SV Zeilsheim | 1:0 |
Germany