| 7. Round | 18/10/1980 | BSG Chemie Leipzig | - | BSG Chemie Zeitz | 1:0 | ||||
| 8. Round | 26/10/1980 | BSG Stahl Blankenburg | - | BSG Chemie Leipzig | 1:1 | ||||
| 9. Round | 08/11/1980 | BSG Chemie Leipzig | - | BSG MK Sangerhausen | 1:0 | ||||
| 10. Round | 15/11/1980 | Chemie Schönebeck | - | BSG Chemie Leipzig | 1:3 | ||||
| 11. Round | 22/11/1980 | BSG Chemie Leipzig | - | BSG Stahl Nordwest Leipzig | 4:3 | ||||
| 12. Round | 29/11/1980 | BSG Chemie Leipzig | - | ASG Vorwärts Dessau | 1:3 | ||||
| 18. Round | 21/03/1981 | BSG Chemie Zeitz | - | BSG Chemie Leipzig | 1:1 | ||||
| 20. Round | 03/04/1981 | BSG MK Sangerhausen | - | BSG Chemie Leipzig | 1:1 | ||||
| 21. Round | 11/04/1981 | BSG Chemie Leipzig | - | Chemie Schönebeck | 4:0 |  |
|||
| 22. Round | 16/04/1981 | BSG Stahl Nordwest Leipzig | - | BSG Chemie Leipzig | 1:3 |
Germany