| 1. Round | 06/08/2021 | MSV 1919 Neuruppin | - | Victoria Seelow | 4:0 | ||||
| 2. Round | 13/08/2021 | Hertha Zehlendorf | - | MSV 1919 Neuruppin | 4:0 | ||||
| 3. Round | 18/08/2021 | MSV 1919 Neuruppin | - | SC Staaken | 1:4 | ||||
| 4. Round | 22/08/2021 | FC Mecklenburg Schwerin | - | MSV 1919 Neuruppin | 3:2 | ||||
| 6. Round | 11/09/2021 | Brandenburger SC Süd | - | MSV 1919 Neuruppin | 1:1 | ||||
| 7. Round | 18/09/2021 | MSV 1919 Neuruppin | - | Greifswalder FC | 0:2 | ||||
| 8. Round | 26/09/2021 | TSG Neustrelitz | - | MSV 1919 Neuruppin | 1:1 | ||||
| 10. Round | 16/10/2021 | Rostocker FC | - | MSV 1919 Neuruppin | 7:0 | ||||
| 11. Round | 23/10/2021 | MSV 1919 Neuruppin | - | Hansa Rostock II | 4:2 |
Germany