| 1. Round | 06/08/2022 | RKC Waalwijk | - | FC Utrecht | 2:2 | ||||
| 2. Round | 13/08/2022 | FC Utrecht | - | SC Cambuur | 0:0 | ||||
| 3. Round | 20/08/2022 | FC Emmen | - | FC Utrecht | 3:2 | ||||
| 4. Round | 28/08/2022 | FC Utrecht | - | AFC Ajax | 0:2 | ||||
| 5. Round | 02/09/2022 | Fortuna Sittard | - | FC Utrecht | 3:4 | ||||
| 6. Round | 11/09/2022 | FC Utrecht | - | Vitesse | 1:0 | ||||
| 7. Round | 16/09/2022 | FC Utrecht | - | NEC Nijmegen | 0:0 | ||||
| 8. Round | 02/10/2022 | SBV Excelsior | - | FC Utrecht | 0:1 | ||||
| 9. Round | 09/10/2022 | FC Utrecht | - | AZ Alkmaar | 1:2 |  |
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| 10. Round | 16/10/2022 | PSV Eindhoven | - | FC Utrecht | 6:1 |
France