| 1. Round | 24/07/2015 | MSV Duisburg | - | 1. FC Kaiserslautern | 1:3 | ||||
| 3. Round | 16/08/2015 | MSV Duisburg | - | Arminia Bielefeld | 2:2 | ||||
| 4. Round | 22/08/2015 | Karlsruher SC | - | MSV Duisburg | 2:0 | ||||
| 7. Round | 20/09/2015 | MSV Duisburg | - | FSV Frankfurt | 0:1 | ||||
| 8. Round | 23/09/2015 | MSV Duisburg | - | Eintracht Braunschweig | 0:5 | ||||
| 9. Round | 26/09/2015 | 1. FC Union Berlin | - | MSV Duisburg | 3:2 |  |
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| 13. Round | 01/11/2015 | TSV 1860 München | - | MSV Duisburg | 1:0 | ||||
| 16. Round | 29/11/2015 | MSV Duisburg | - | SV Sandhausen | 3:0 | ||||
| 18. Round | 13/12/2015 | 1. FC Kaiserslautern | - | MSV Duisburg | 2:0 | ||||
| 24. Round | 02/03/2016 | FSV Frankfurt | - | MSV Duisburg | 3:3 | ||||
| 26. Round | 12/03/2016 | MSV Duisburg | - | 1. FC Union Berlin | 2:1 |  |
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| 27. Round | 18/03/2016 | SC Paderborn 07 | - | MSV Duisburg | 0:0 | ||||
| 28. Round | 01/04/2016 | MSV Duisburg | - | 1. FC Heidenheim 1846 | 0:2 | ||||
| 30. Round | 15/04/2016 | MSV Duisburg | - | TSV 1860 München | 2:1 | ||||
| 31. Round | 22/04/2016 | SC Freiburg | - | MSV Duisburg | 3:0 | ||||
| 33. Round | 08/05/2016 | SV Sandhausen | - | MSV Duisburg | 2:2 | |
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| 34. Round | 15/05/2016 | MSV Duisburg | - | RB Leipzig | 1:0 |
Germany