| 3. Round | 28/08/2021 | TB Uphusen | - | TuS Bersenbrück | 2:1 | ||||
| 6. Round | 19/09/2021 | Rotenburger SV | - | TuS Bersenbrück | 1:1 | ||||
| 7. Round | 26/09/2021 | TuS Bersenbrück | - | Kickers Emden | 2:1 |  |
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| 8. Round | 03/10/2021 | FC Hagen/Uthlede | - | TuS Bersenbrück | 1:0 | ||||
| 9. Round | 10/10/2021 | TuS Bersenbrück | - | SC Spelle-Venhaus | 3:0 | ||||
| 10. Round | 17/10/2021 | TuS Bersenbrück | - | Blau-Weiß Lohne | 2:0 | ||||
| 11. Round | 24/10/2021 | MTV Eintracht Celle | - | TuS Bersenbrück | 5:3 | ||||
| 15. Round | 21/11/2021 | TuS Bersenbrück | - | Rotenburger SV | 2:2 |  |
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| 17. Round | 05/12/2021 | TuS Bersenbrück | - | FC Hagen/Uthlede | 7:1 | |
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| 16. Round | 11/12/2021 | Kickers Emden | - | TuS Bersenbrück | 2:0 |
Germany