| 7. Round | 19/08/2022 | 1. FC Schweinfurt 05 | - | Bayern München II | 2:0 | ||||
| 8. Round | 23/08/2022 | 1. FC Schweinfurt 05 | - | SpVgg Greuther Fürth II | 1:0 | ||||
| 9. Round | 26/08/2022 | TSV Aubstadt | - | 1. FC Schweinfurt 05 | 1:0 | ||||
| 10. Round | 02/09/2022 | 1. FC Schweinfurt 05 | - | Würzburger Kickers | 2:5 | ||||
| 11. Round | 10/09/2022 | SpVgg Hankofen-Hailing | - | 1. FC Schweinfurt 05 | 3:3 | ||||
| 12. Round | 16/09/2022 | 1. FC Schweinfurt 05 | - | 1. FC Nürnberg II | 1:3 | ||||
| 13. Round | 23/09/2022 | FC Pipinsried | - | 1. FC Schweinfurt 05 | 0:2 | ||||
| 14. Round | 30/09/2022 | 1. FC Schweinfurt 05 | - | VfB Eichstätt | 2:0 | ||||
| 15. Round | 03/10/2022 | SpVgg Ansbach | - | 1. FC Schweinfurt 05 | 2:2 | ||||
| 16. Round | 07/10/2022 | 1. FC Schweinfurt 05 | - | Türkgücü München | 0:1 | ||||
| 17. Round | 15/10/2022 | DJK Vilzing | - | 1. FC Schweinfurt 05 | 1:2 | ||||
| 18. Round | 22/10/2022 | 1. FC Schweinfurt 05 | - | Viktoria Aschaffenburg | 1:1 | ||||
| 19. Round | 29/10/2022 | SpVgg Unterhaching | - | 1. FC Schweinfurt 05 | 4:3 | ||||
| 20. Round | 05/11/2022 | 1. FC Schweinfurt 05 | - | TSV 1896 Rain | 1:3 | ||||
| 21. Round | 12/11/2022 | TSV Buchbach | - | 1. FC Schweinfurt 05 | 2:2 |
Germany