| 4. Round | 24/04/2022 | Viktoria Clarholz | - | SpVgg Vreden | 4:1 |  |
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| 2. Round | 28/04/2022 | TuS Ennepetal | - | SpVgg Vreden | 2:2 | |
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| 5. Round | 01/05/2022 | SpVgg Vreden | - | Westfalia Herne | 5:0 | |
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| 7. Round | 08/05/2022 | SpVgg Vreden | - | Preußen Münster II | 2:0 | |
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| 8. Round | 15/05/2022 | SG Finnentrop/Bamenohl | - | SpVgg Vreden | 1:2 | |
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| 1. Round | 19/05/2022 | SpVgg Vreden | - | Holzwickeder SC | 3:2 | |
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| 10. Round | 29/05/2022 | SpVgg Vreden | - | TuS Haltern | 7:2 | ||||
| 11. Round | 06/06/2022 | RSV Meinerzhagen | - | SpVgg Vreden | 1:0 |
Germany