| Group G | 14/09/2021 | Sevilla FC | - | RB Salzburg | 1:1 |  |
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| Group G | 29/09/2021 | RB Salzburg | - | Lille OSC | 2:1 | ||||
| Group G | 20/10/2021 | RB Salzburg | - | VfL Wolfsburg | 3:1 | ||||
| Group G | 02/11/2021 | VfL Wolfsburg | - | RB Salzburg | 2:1 | ||||
| Group G | 23/11/2021 | Lille OSC | - | RB Salzburg | 1:0 | |
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| Group G | 08/12/2021 | RB Salzburg | - | Sevilla FC | 1:0 | ||||
| Round of 16 | 16/02/2022 | RB Salzburg | - | Bayern München | 1:1 | ||||
| Round of 16 | 08/03/2022 | Bayern München | - | RB Salzburg | 7:1 |
Austria