| 4. Round | 01/09/2021 | SV Rot-Weiss Hadamar | - | Viktoria Griesheim | 1:1 |  |
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| 5. Round | 05/09/2021 | SV Zeilsheim | - | Viktoria Griesheim | 4:0 | ||||
| 6. Round | 11/09/2021 | Viktoria Griesheim | - | VfB Ginsheim | 3:0 | |
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| 7. Round | 15/09/2021 | Viktoria Griesheim | - | Rot-Weiß Walldorf | 3:2 | ||||
| 9. Round | 25/09/2021 | TuS Dietkirchen | - | Viktoria Griesheim | 1:3 | ||||
| 11. Round | 02/10/2021 | Viktoria Griesheim | - | SC Waldgirmes | 1:3 | ||||
| 13. Round | 16/10/2021 | Viktoria Griesheim | - | Türk Gücü Friedberg | 0:0 | ||||
| 14. Round | 24/10/2021 | FV Bad Vilbel | - | Viktoria Griesheim | 0:3 | ||||
| 15. Round | 27/10/2021 | Viktoria Griesheim | - | SV Zeilsheim | 4:1 | |
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| 16. Round | 30/10/2021 | Viktoria Griesheim | - | FV Bad Vilbel | 2:3 | ||||
| 17. Round | 07/11/2021 | Türk Gücü Friedberg | - | Viktoria Griesheim | 2:3 | ||||
| 18. Round | 13/11/2021 | Viktoria Griesheim | - | Hessen Dreieich | 1:3 | ||||
| 19. Round | 20/11/2021 | SC Waldgirmes | - | Viktoria Griesheim | 2:0 | ||||
| 20. Round | 27/11/2021 | Viktoria Griesheim | - | TuS Dietkirchen | 1:2 | ||||
| 22. Round | 11/12/2021 | VfB Ginsheim | - | Viktoria Griesheim | 4:3 |
Germany