| 2. Round | 20/08/2022 | RB Leipzig [Youth B] | - | Werder Bremen [Youth B] | 6:2 |  |
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| 3. Round | 27/08/2022 | FC Viktoria 1889 Berlin [Youth B] | - | RB Leipzig [Youth B] | 1:3 | ||||
| 4. Round | 03/09/2022 | RB Leipzig [Youth B] | - | Hansa Rostock [Youth B] | 1:2 | |
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| 5. Round | 10/09/2022 | Dynamo Dresden [Youth B] | - | RB Leipzig [Youth B] | 1:2 | ||||
| 6. Round | 17/09/2022 | RB Leipzig [Youth B] | - | Hannover 96 [Youth B] | 4:1 | ||||
| 7. Round | 02/10/2022 | Chemnitzer FC [Youth B] | - | RB Leipzig [Youth B] | 2:0 | |
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| 8. Round | 08/10/2022 | RB Leipzig [Youth B] | - | Hertha BSC [Youth B] | 3:2 |  |
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| 9. Round | 29/10/2022 | FC St. Pauli [Youth B] | - | RB Leipzig [Youth B] | 1:3 | |
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| 11. Round | 12/11/2022 | Hamburger SV [Youth B] | - | RB Leipzig [Youth B] | 2:2 | ||||
| 12. Round | 19/11/2022 | RB Leipzig [Youth B] | - | SV Meppen [Youth B] | 6:1 | ||||
| 14. Round | 10/12/2022 | RB Leipzig [Youth B] | - | FC Carl Zeiss Jena [Youth B] | 5:1 | ||||
| 15. Round | 25/02/2023 | 1. FC Magdeburg [Youth B] | - | RB Leipzig [Youth B] | 1:1 | |
Germany